Department of Pathology, ESIC MC and PGIMSR, Rajajinagar, Bangalore, India
Research Article
Clinicopathological Study of Barrett’s Esophagus
Author(s): Pawan Khandre*, Vani B.R, Anvita N, Deepak Kumar B and Srinivasa Murthy V
Introduction: Barrett’s esophagus (BE) is a premalignant esophageal lesion found in 10% of patients with Gastroesophageal Reflux Disease (GERD) and 2% of the general population. The endoscopic appearance of salmon-colored mucosa measuring ≥1 cm proximal to the gastroesophageal junction, combined with intestinal metaplasia (IM) on biopsy, is diagnostic. IM that contains goblet cells has a higher risk for esophageal cancer. The most common histopathological finding is the replacement of squamous epithelium by gastric or intestinal-type metaplastic columnar epithelium. This study aims to evaluate the various histomorphological features of BE and their association with clinical features and endoscopic findings.
Materials and methodology: This study is a cross-sectional analysis conducted in the histopathology section of the Departm.. View More»
