Department of Diagnostic Pathology, Shimada General Medical Center, Shimada, Shizuoka, Japan
Case Report
A Simple Cyst of the Testis was Found Incidentally during Castration for Prostatic Cancer
Author(s): Mitsuhiro Tachibana*
Simple Cysts (SCs) within the testes are rare in adults. The testicular SC lining
comprises mesothelial cells. This report presents a case involving the accidental
discovery of a castration-worthy SC in the right testis of a Japanese man in his 90s
who was diagnosed with prostatic adenocarcinoma. Microscopic analysis revealed
that the cystic wall was covered with flat to cuboidal mesothelial cells. Immunohistochemistry
demonstrated mesothelial cell positivity for calretinin, Wilms Tumor
1 (WT-1), Hector Battifora Mesothelial Epitope-1 (HBME-1), and Cyclin-Dependent
Kinase Inhibitor p16 (p16INK4a). Notably, no Human Papillomavirus (HPV) in situ hybridization was detected. This report outlines an exceptionally rare instance of
a simple cyst within the testis, suggesting the possibility of its origin from ectopic
rete testis epithelium. This marks the .. View More»
