Department of Anaesthesia, University Hospital of North Durham, CDDFT NHS Foundation Trust, UK
Research Article
Attenuation of Hypotension due to Spinal Anaesthesia with Ondansetron in Parturients Undergoing Caesarean Section: An Observational Study
Author(s): Arun Philip Varghese, Sunil Manikkath, Sunil Raveendran, Anisha Nakulan and Anoop PV*
BACKGROUND
About seventy to eighty percent of patients experience hypotension during caesarean section conducted under spinal anaesthesia. Bezold Jarisch Reflex is hypothesized to be one of the main factors contributing to this cycle of deleterious hypotension and bradycardia. Studies suggests that ondansetron (5-HT3 receptor antagonist) can antagonize this cycle of events from the receptor level and can prevent it.
AIMS
To study the efficacy of prophylactic intravenous ondansetron in preventing hypotension due to spinal anaesthesia and to compare the hemodynamic parameters among two study groups undergoing planned elective caesarean section.
METHODS
It was a prospective comparative study and out of sixty subjects undergoing elective caesarean section, thirty were those received intra.. View More»
