Usage of Systemic Therapies in Oral Lichen Planus


Rithanya P and Jayanth Kumar Vadivelu*

Introduction: Oral lichen planus is a relatively common chronic inflammatory immunological reaction in which the epidermal or the epithelial basal cell layer damage produces mucocutaneous lesions of varying types. It varies in appearance from keratotic (reticular or plaque like) to erythematous or the ulcerative type. Even though the etiology for oral lichen planus is unknown, the immune system has a primary role in the development of the disease. The principal aim of treating oral lichen planus would be resolving the painful symptoms of the oral lesions and the long term follow-up to counter the chances of transformation in the course of the disease.

Aim of the Study: The aim of the present study was to analyse the incidence rate in the usage of systemic therapies in oral lichen planus. Thereby providing better treatment options for a better outcome.

Materials and Methods: Retrospective analysis of all the cases (Oral lichen Planus under systemic therapies) was retrieved among the overall data of patients visiting Saveetha Dental College. The data was entered in Excel Spreadsheets. And the collected data was analysed using SPSS software version 19. Chi square test was used to statistically evaluate the results.

Result: In the present study carried out, it was found that corticosteroids was used in about (113.9 %) along with combinations of other medications such as histamine, steroid sparing and other supplement agents. And anti-histamine was used in (176.4 %) along with a combination of supplements. And only supplements were administered in about (70 %) of the patients. The results obtained were statistically significant (p < 0.005).

Conclusion: From the present study, it was found that anti histamines were the most commonly used drugs in combinations, followed by corticosteroid and other supplement therapy.