Shilpa Anand Hakki

There is an alarming increase in the incidence of fever with thrombocytopenia especially during monsoon and peri-monsoon period. Infections with protozoa, bacteria and viruses can cause thrombocytopenia with or without disseminated intravascular coagulation. Commonly, dengue, malaria, scrub typhus and other rickettsial infections, meningococci, Leptospira and certain viral infections present as fever with thrombocytopenia. Occasionally, these patients can go on to develop a stormy course with multiorgan dysfunction requiring intensive care unit admission associated with high morbidity and mortality. The aim of this study is to analyse the clinical outcomes of fever with thrombocytopenia.
A prospective three months study was undertaken in a super specialty hospital in Dharwad. Total 461 patients were studied who presented with fever with thrombocytopenia. Inclusion Criteria- Patients with acute history of fever were included in the study. Clinical profile, relevant investigations, residential prevalence and related complications were studied. Settings- This was a prospective study of three months duration, which was undertaken a super specialty Hospital, Dharwad.
Out of 461 patients who presented with fever with thrombocytopenia, 331 were seropositive for dengue, 123 patients had unspecified viral fever while 6 patients were diagnosed to have malaria and one patient had mixed infection of dengue and malaria.
Among 461 patients with fever with thrombocytopenia, dengue was the most common cause followed by unspecified viral fever and then malaria. MODS is the most common complication in this study.