TOUCH IMPRINT CYTOLOGY- A RAPID INTRAOPERATIVE DIAGNOSTIC METHOD FOR OCULAR SURFACE SQUAMOUS NEOPLASIA

Abstract

Gopeswari Hota1, Bidisha Mahapatra2, Sharmistha Behera3

BACKGROUND
The technique of imprint cytology is a simple, cost effective, rapid technique of intraoperative diagnosis of tumours. It plays a significant role in the rapid diagnosis of the lesions in centres with less developed infrastructure.
Objectives of this study were to analyse the accuracy of imprint cytology and thereby to evaluate its diagnostic utility.
MATERIALS AND METHODS
The prospective study was carried out in a tertiary care hospital. It included 12 cases of ocular surface squamous neoplasia. The cytodiagnosis was correlated with histopathological (HP) diagnosis to evaluate the accuracy of imprint cytology.
RESULTS
Maximum lesions were of invasive squamous cell carcinoma (50%) followed by intraepithelial neoplasms including dysplasias (33.3%) and carcinoma in situ (16.6%). Overall accuracy of detecting type of lesion was 83.33%. Total discordance with HP diagnosis was 16.6%.
CONCLUSION
Intraoperative diagnosis using imprint cytology provides a rapid and efficient means of pathological assessment which in experienced hand, is capable of obtaining a high degree of accuracy.

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