TOBACCO USE: A STUDY OF ITS CYTOGENETIC AND DNA DAMAGING ABILITY

Abstract

Suchitra A. Shetty 1 , Shreesha Khandige 2

From times unknown tobacco and its consumable other forms have been fancied by man. Men suffered consequences but not until the second half of the twentieth century its side effects were studied. In the turn of the century cancer turned out to be the top killer worldwide and the tobacco use was found to be the main culprit of the above said condition. The study mainly aims to assess the harmful effects in the oral epithelial cells with each passing years. The sample size consisted of 60 people who were divided into four groups. All the volunteers were between 25 to 50 years. It is very clear in the study that the risk of having a carcinoma increases with the time of consumption of tobacco. The micronucleus study and the comet assay can be used to investigate and screen the population at risk.

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