Virendra Vijay Saoji1, Yogeshree Rajendra Deshmukh2
Vitiligo is an acquired chronic pigmentation disorder that causes depigmentation of the skin corresponding to a substantial loss of functioning epidermal and sometimes hair follicle melanocytes. Histologically, it is characterised by degeneration and disappearance of melanocytes in the involved skin and not infrequently in the pigment epithelium of the eyes, leptomeninges and inner ear.
MATERIALS AND METHODS
The study was conducted on 46 patients of localised vitiligo attending outpatient department. The patients fulfilling the inclusion and exclusion criteria were divided into two groups alternately, 23 patients in each group. The assessment of effectiveness was done using VASI scale. The follow up of patients were done on 2nd, 4th and 6th week after initiation of treatment.
We observed 46 patients and they showed moderate response.
Both Tacrolimus ointment and fluticasone propionate were moderately effective in localised vitiligo. But, this did not show complete clearance of the patches in all patients.
Vitiligo, Tacrolimus, Fluticasone Propionate.