Ishwar Sidappa Hasabi1, Basith Lateef Kardkal2, Uday Subhash Bande3
Diabetes has now become the most common single cause of end-stage renal disease. Diabetic Kidney Disease (DKD) is a life-threatening and irreversible microvascular complication characterised by presence of persistent proteinuria, hypertension and progressive decline in renal function. Early detection and risk reduction measures can prevent diabetic nephropathy. Screening for microalbuminuria will allow early identification of patients with nephropathy provide an opportunity for early treatment, which has been shown to preserve renal function and thus prevent morbidity and mortality from diabetic nephropathy.
The aim of the study is to study the relation between duration of diabetes and nephropathy.
MATERIALS AND METHODS
120 patients with type 2 diabetes mellitus admitted to medical wards, KIMS, Hubli, over a period of one year satisfying the inclusion and exclusion criteria were enrolled for the study. 40 normal healthy adults were included in the control group. It’s a cross-sectional study and patients were enrolled by random sampling method. All the selected patients were subjected to detailed history and complete physical examination and data collected was noted in a predesigned pro forma.
Study participants were subdivided based on duration of diabetes into <5 years, 5-10 years and >10 years. Their mean age of onset of diabetes was 54.5 (± 10) years. Microalbuminuria was present in 45% (n=54) of diabetics, retinopathy 35.8% (n=43) and both increased with increase in duration of diabetes (p value 0.003 and 0.001, respectively) (Table 3 and 4). Prevalence of hypertension was 51.7% in present study group and was significantly associated with duration of diabetes.
This study highlighted the prevalence of microalbuminuria and retinopathy in type 2 diabetes subjects. Microalbuminuria increases with increase in duration of diabetes. Screening for microalbuminuria will allow early detection of patients with nephropathy.
Diabetes, Duration of Diabetes, Nephropathy.