Abstract

STUDY ON VEP CHANGES IN PATIENTS WITH TYPE II DIABETES WITHOUT RETINOPATHY

Author(s): Venkatesh S BACKGROUND In patients with diabetes neurofunctional changes occur much earlier than clinically detectable changes, detection of these changes will help us in early identification of diabetic retinopathy leading to a better management and prognosis. Aim- The aim and objectives of the study were to observe the pattern reversal VEP in a group of patients with Type 2 Diabetes Mellitus without Retinopathy and to correlate it with duration of Diabetes and HbA1c levels. MATERIALS AND METHODS This prospective hospital based cross sectional study was undertaken in 40 patients with type 2 DM referred from the department of diabetology. 40 age and sex matched control subjects were taken from master health check-up attending our hospital. All patients underwent a comprehensive ophthalmic examination, and the pattern VEPs was recorded. RESULTS There was a statistically significant difference in p100 latencies. Positive correlation was observed between the duration of diabetes, HbA1c levels and VEP changes. CONCLUSION Neurofunctional changes occur in patients with type 2 diabetes earlier than the clinically detectable microvascular changes. So, it is important to screen high risk patients with diabetes both clinically as well as by electrophysiologically.