Saroja Adapa1, Sridevi Pottekula2
Normal labour is a difficult processes characterised by uterine action leading to cervical dilation and effacement followed by delivery of the foetus. Any procedure or drug, which decreases the duration of labour is a boon for both patient and obstetrician.
The aim of the study is to evaluate and compare the efficacy of drugs drotaverine and valethamate bromide in shortening the active phase of cervical dilations to decrease the duration of labour without affecting foetal outcome.
MATERIALS AND METHODS
This comparative study was done in the Department of OBG, Government Maternity Hospital (GMH), Sultan Bazar, Hyderabad, from January 2015 to June 2015 on 200 patients. The patients were randomly divided into two groups and drugs were given when cervix is 3-4 cm dilated and time duration till full dilation was noted. Group D- This group includes cases, which were given intravenous drotaverine 40 mg and repeated if necessary after two hours upto maximum of 3 injections. Group V- This group includes cases, which were given intravenous valethamate 8 mg every hour up to maximum of 6 injections. The patients and foetus were monitored by partogram.
In the present study, D-group injection dilatation interval in primigravida and second gravida was 210 minutes and 165 minutes respectively compared to V-group with 273 minutes and 203 minutes for primigravida and second gravida, respectively. The average cervical dilatation in primi and second gravida in D-group were 2 cm/hr. and 2.5 cm/hr. respectively and 1.5 cm/hr. and 2 cm/hr. in primi and second gravida in V-group, respectively. There is no significant difference in duration of second stage, third stage, side effects and Apgar score in both groups. Drotaverine is more effective than valethamate bromide.
Though both drugs can be used for shortening of active phase of labour, drotaverine is more effective. Both drugs have no side effects on the foetus.