Susil Kumar R1, Bhupati Bhusan Das2, Sushanta Kumar Das3, Niranjan Sahoo4, Laxmidhar Padhy5, Mohammad Asfak Ahmed6
Benign breast diseases constitute a heterogeneous group of lesions including developmental abnormalities, inflammatory lesions, epithelial and stromal proliferations. The aim of my study is to determine the correlation between hyperlipidemia or dyslipidemia and benign breast diseases. Although a lot of work has been done regarding the serum lipid profile alteration in malignant breast diseases, a very little work has been done on serum lipid profile alteration in benign breast diseases especially in developing country like India where the dietary habits of people have changed towards the western style in the last few decades. The study was conducted on 50 patients who came to the OPD of MKCG Medical College & Hospital, Brahmapur, Odisha for treatment during the period from August 2012 to July 2014. Four types of benign breast disease patients namely fibroadenoma, fibroadenosis, breast abscess and mastalgia were included in the study. The patients underwent thorough clinical breast examination, Fine Needle Aspiration Cytology, & biopsy. Fasting venous blood sample of fifty normal subjects (controls) and 50 patients of benign breast disease were investigated for serum total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, very low density lipoprotein cholesterol and triglyceride. Comparison was made between serum lipid profile of various types of benign breast disease and controls. It was observed that there was significant rise in serum total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglyceride. However no significant difference was found in low density lipoprotein cholesterol in different groups of benign breast disease and controls.