Author(s): Suresh C. H1, Chethan Kumar K. L2
Chronic kidney disease (CKD) as the name goes is a condition wherein there is a progressive loss in renal function over a period of months to years. This disease has now emerged to be a major public health issue worldwide with the prevalence shooting up to new highs during the recent years. 1 Indeed, it has been estimated recently that the age-adjusted incidence rate of End Stage Renal Disease (ESRD) in India to be 229 per million population. 2 Previously hyperuricemia was thought to be a consequence of renal impairment but recent studies have shown that hyperuricemia itself can be an independent risk factor for the development of CKD. Most of the uric acid generated in the body is excreted through the kidney. So as expected, hyperuricemia is a frequent accompaniment of chronic kidney disease. 3,4 Although high uric acid level is often seen in CKD patients, it was not clear whether hyperuricemia per se is an individual risk factor in development and progression of CKD. 5 But recent studies show that high uric acid level can be an independent risk factor for the development of chronic kidney disease. 6 Uric acid can also be used as a marker of CKD.7 In the following study, the various factors influencing the levels of uric acid have been analyzed and correlated with the data obtained from the subjects under study. The main aim of this study is to evaluate the factors causing hyperuricemia, which will help to stall the progression of CKD at an early stage thereby increasing the longevity and reducing the morbidity for the patients.