Author(s): Mohammed Aslam Shaikh1, Bhanuprakash P2
Metabolic Syndrome (MS) is considered as a major public health concern since the prevalence has reached epidemic proportions in the past decade. The Platelet-to-Lymphocyte Ratio (PLR) has recently emerged as a novel inflammatory biomarker, which has been used in many diseases for predicting inflammation and mortality. Hence, the present study was done to study the association between the platelet-to-lymphocyte ratio and presence of metabolic syndrome.
MATERIALS AND METHODS
50 patients with metabolic syndrome were included in the study. 50 age and sex matched healthy individuals were included as the control group. The study was carried out over a period of 1 year from October 2015 to September 2016. The new international diabetic federation (IDF) criteria was used to make a diagnosis of metabolic syndrome. Platelet-to-lymphocyte ratio was calculated from the complete blood count.
The mean age of the patients in the study group was 52.62 ± 15.42 years. The mean hs-CRP was significantly higher in patients with MS (4.0982 ± 2.2971) when compared with patients without MS (1.449 ± 0.9657) (p<0.005). Mean PLR was also higher in patients with MS (194.64 ± 72.13) when compared with patients without MS (92.72 ± 35.32) (p<0.005).
As platelet-to-lymphocyte ratio is an easily available and cheap inflammatory biomarker, it can be used as a marker of metabolic syndrome.
Platelet-to-Lymphocyte Ratio, Metabolic Syndrome, High-Sensitive C-Reactive Protein