STUDY OF PHARMACO THERAPEUTIC CONSIDERATIONS IN THE MANAGEMENT OF HEART FAILURE

Abstract

Souris Kondaveti1, Bhuvaneshwari2, Balakrishna Namala3

BACKGROUND AND OBJECTIVES: Congestive heart failure (CHF) continues to be a major clinical and public health problem. Conflicting data exists about its rate of occurrence in general population, relative frequencies of predisposing heart diseases and the prognosis of the patient. In the present study, gender aspects, age wise distribution, drug distribution pattern were assessed in these patients

MATERIALS AND METHODS: A total number of 100 patients from the medical outpatient department of medicine, M.G.M. Hospital Warangal were enrolled into the study. All male and female patients between 30 to 85 years of age, diagnosed with heart failure falling into the category of functional New York Heart Association (NYHA) class II or III with left ventricular ejection fraction (LVEF) ≤35% were included in the study.

RESULTS: Of the 100 subjects studied 55 (40-75 yr) were male and 45 (35-73 yr) were female. 94 patients presented with ischemic heart failure compared to only 6 patients with non-ischemic heart failure. Out of total subjects enrolled, 61 were put on Digoxin, 71 on Diuretics, 47 on ACEI, 20 on Beta Blocker (Carvedilol), 30 on Nitrates, 64 on Anticoagulants, 19 on Statins.

CONCLUSION: The incidence of heart failure was more in advanced age groups and slightly more common in males. Ischemic heart disease accounted for heart failure in majority of patients in our study we found that Digoxin, Diuretics, ACEI and Anticoagulants followed by Nitrates, Beta blockers and Statins were the most prescribed medications in the management of heart failure

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