STUDY OF OCULAR RISK FACTORS FOR PRIMARY OPEN-ANGLE GLAUCOMA

Abstract

Pragati Garg1, Monalisa Jha2, Luxmi Singh3, Ishani Kawatra4, Bishan Bihari Lal5

PURPOSE
Glaucoma causes irreversible progressive visual impairment. Increased intraocular pressure remains an important primary and prognostic risk factor for primary open-angle glaucoma (POAG), but its association with other risk factors is also present. This study was conducted to assess the relationship between potential ocular risk factors and the development of POAG to aid in early diagnosis.
DESIGN
Hospital based case control study.
METHODS
A case control study was conducted on 134 cases of POAG (Group 1) and 134 normal individuals without POAG (Group 2). Ocular risk factors like axial length, central corneal thickness, intraocular pressure, iris colour, cup-disc ratio, refractive status of eye were studied in both the groups and compared using Chi-square test.
RESULTS
POAG cases (Group 1) had thin cornea (p=0.005) and longer axial length (p<0.05) as compared to Group 2. Myopia (p=0.268) was more common than hypermetropia in POAG cases with odds ratio higher than unity (odds ratio=3.03).
CONCLUSION
A thin cornea and longer axial length were proved as ocular risk factors for POAG. Iris colour is not collaborative as risk factor. Myopia was more common in POAG cases.

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