Author(s): Mudunuri Sita Rama Lakshmi1, Yeedi Ramya Subhashini2, K. S. R. Swami3
Chronic kidney disease (CKD) is an irreversible deterioration of renal function, which results from diminished effective functioning of renal tissue. Ensuing impairment of excretory, metabolic and endocrine functions of the kidney leads to the development of clinical syndrome of uraemia. Dyslipidaemia is found in many patients that lead to cardiovascular complication.
MATERIAL AND METHOD
Cases of chronic kidney disease admitted in the medical wards of Konaseema Institute of Medical Sciences from June 2013 to October 2015 were taken for study.
Total cholesterol value in controls and CKD patients are 185.2±24.51 and 187±43.5 mg/dL respectively. Triglyceride values in patients and controls were 174±60.7 and 97±17 mg/dL respectively. HDL values in chronic kidney disease patients are decreased compared to controls, 36±5.1 and 48.8±10.3 mg/dL. VLDL- Significant increase in VLDL was found in CKD patients as compared to controls, 34.88±12.15 and 19.3±3.49 respectively.
LDL values were almost similar in both CKD patients and control group, 116.49±38.34 and 116.8±26.78 respectively.
Lipid abnormalities in chronic kidney disease accelerates the progression of the renal failure and predisposes to atherosclerosis, it is worthwhile detecting and treating hyperlipidaemia in chronic kidney disease patients.