STUDY OF CLINICAL PROFILE OF CEREBRAL VENOUS SINUS THROMBOSIS IN KARNATAKA INSTITUTE OF MEDICAL SCIENCES, HUBLI

Abstract

Sudhindra Babu G. S, Kalinga Bommanakatte Eranaik, Amruth Gujjas

Patients with Cortical venous thrombosis present with varied clinical features and often missed in a plain axial CT Brain. Hence identifying risk factors is important in such patients so that appropriate imaging and early treatment can be initiated. The present study is directed in identifying most common risk factors in patients with CVT in a tertiary care centre. Aim of Study- To study the clinical profile of patients with CVT in a tertiary care hospital in north Karnataka. MATERIALS AND METHODS 78 patients with CVT diagnosed based on imaging aged more than 13 years were included in the study. Each patient underwent necessary investigations including imaging. Detail evaluation of risk factors was done based on history collected and lab parameters. Sample Size- 78. Type of Study- Single centre observational study. RESULTS Cerebral venous sinus thrombosis is most common in young population. Most common affected age group is 21-40 years with mean age of 32±11 years. Incidence of cerebral venous sinus thrombosis is more in males when compared to females. Most common mode of presentation was seizures followed by headache. Most common risk factor for cerebral venous sinus thrombosis is alcohol in males followed by dehydration, peripartum state in females, hyperhomocysteinaemia and tobacco use. Cerebral venous sinus thrombosis was more common following first pregnancy when compared to subsequent pregnancies. Cerebral venous sinus thrombosis in peripartum state was most commonly seen between 7-42 days of delivery. Superior sagittal sinus is the most common sinus involved in cerebral venous Thrombosis. Multiple sinus involvement is associated with greater case fatality rate. Coma at the time of presentation, cerebral venous sinus thrombosis with midline shift, deep cerebral venous sinus thrombosis are predictors of poor outcome in cerebral venous sinus thrombosis. CONCLUSION In our study CVT affected the most productive age group of patients and most common risk factor could be reduced by health education and primary prevention.

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