STUDY OF CLINICAL AND ENDOCRINE PROFILE OF PATIENTS WITH PITUITARY TUMOURS ATTENDING A TERTIARY CARE HOSPITAL

Abstract

Binoy Kumar Mohanty1, Arun Kumar Choudhury2, Anoj Kumar Balirsinha3, Debarchan Jena4, Deepak Kumar Dash5

BACKGROUND
Pituitary tumours are relatively common endocrine tumours. They can present with symptoms related to hormone excess or hormone deficiency. They can also present with compressive symptoms like visual problems and headache.
OBJECTIVE
To study the various clinical presentations and endocrine profile of patients presenting with pituitary tumours to a tertiary care hospital.
DESIGN
Cross sectional study.
MATERIAL AND METHODS
We collected and analysed the clinical data including hormonal status of 33 consecutive patients who presented to our department from March 2014 to February 2016 for evaluation of pituitary tumours.
RESULTS
Majority of the subjects studied belonged to 40-50 years group (33.34%).The most common type of pituitary tumour in our population was non-functioning pituitary tumours (45.45%). The next common cause was somatotroph adenoma (27.27%) followed by prolactinoma (15.15%) and corticotroph adenomas (12.13%). There was significant male predominance (60.60%) among total cases. Among all patients, headache (54.54%) was most common presentation followed by features related to hormone excess (51.51%).
CONCLUSIONS
Pituitary tumours can present with variety of symptoms. A detailed endocrine workup is essential in each case to reach at correct diagnosis. In our cohort, non-functioning pituitary tumour was the most common tumour subtype.

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