SPECTRUM OF PATHOLOGIC LESIONS IN LYMPH NODE BIOPSIES- A RETROSPECTIVE STUDY

Abstract

Amit Kumar Tiwari1, Amit Kumar Bhardwaj2, Tapas Ranjan Behera3, Maikal Kujur4, Amar Bahadur Singh5

BACKGROUND
The aim of this study is to analyse histopathologic spectrum of various neoplastic and nonneoplastic diseases affecting cervical, axillary, inguinal, mesenteric and submandibular lymph nodes.
MATERIALS AND METHODS
The retrospective study conducted from March 2003 to August 2014 in Chhattisgarh Institute of Medical Sciences, India. The study included 140 cases of lymph node biopsies received in the Pathology Department.
RESULTS
Out of 140 lymph node biopsies received, 51 (36.42%) were from cervical region, 12 cases (8.57%) from axillary region, 28 from mesenteric region, 9 were from inguinal region, 8 from submandibular region and 32 from unknown region collected from all age groups. Most common condition involving the lymph node was found to be tuberculosis (41) followed by Hodgkin lymphoma (18) and granulomatous lesion other than tuberculosis (17) followed by reactive hyperplasia. Lymphoma other than Hodgkin and chronic nonspecific lymphadenitis had equal incidence (each presented by 13 cases). Metastasis and sinus histiocytosis were seen in the descending order of frequency.
CONCLUSION
Lymph node involvement by nonneoplastic diseases (granulomatous and nonspecific) (58+39) is much more common than the neoplastic diseases (43), tuberculosis (41) being the predominant.

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