Role of Transvaginal Ultrasonography in Assessing Depth of Myometrial Invasion among Patients with Uterine Cancer

Author(s): Vinay N.V.P.1 , Indra Neil Mekala2 , Ch. Dinesh3 , D. Venkata Ramana Rao4

BACKGROUND In some parts of world endometrial cancer (En-Ca) accounts for 4-8% of all cancers, fourth most common cancer after breast, colon and lung cancers. In others it is less common, lowest rates in India and south-east Asia. Morbidity and mortality are low because most patients present at early stage for abnormal bleeding though pain also could be there. Recently there is an increase in the incidence in India due to changing lifestyles and food habits. METHODS This prospective study has been conducted in the Department of Radiodiagnosis, GSL General Hospital and Medical College, Rajahmundry, from January 2016 to June 2017. A total of 33 consecutive histologically proven early stages of endometrial carcinoma patients were included in the study. Transvaginal ultrasound examinations were performed by a radiologist using Philips HD7XE machine with 5.0 to 7.5 MHz curvilinear array transducer probe. RESULTS Transvaginal ultrasonography was found to have a sensitivity of 93.75%, specificity of 88.23%, positive predictive value of 88.23% and negative predictive value of 93.75% in diagnosis of stage 1a. On the other hand, sensitivity of 88.23%, specificity of 93.75%, positive predictive value of 93.75% and negative predictive value of 88.23% in diagnosing stage 1b. CONCLUSIONS Transvaginal sonography has high sensitivity, specificity, PPV and NPV in detecting depth of myometrial invasion of early stages of uterine cancer. Transvaginal sonography is much more operator dependent, but is less expensive and more widely available.