RED BLOOD CELL ABNORMALITIES IN DECOMPENSATED CHRONIC LIVER DISEASE (DCLD)

Abstract

G. Anbazhagan1, P. Mohan Raj2, S. Kalaivalli3, Vishnuprasanth4

BACKGROUND: Liver plays an important role in normal erythropoiesis, especially in formation and destruction of RBC’s. Chronic liver diseases are frequently associated with hematological abnormalities. Anemia of diverge etiology occurs in about 75% patients with DCLD (36). This can ultimately culminate in grave complications.

AIM OF THE STUDY: To detect various abnormalities in Red Blood Cells and to assess the type of anemia in DCLD

METHODS: The study was conducted in 50 patients of DCLD, in Meenakshi Medical College. A detailed History, clinical examination and also Ultrasound Abdomen, GI endoscopy to establish DCLD and complete Red Blood Cell assessment was done

RESULTS AND OBSERVATION: Among the 50 patients, 40 patients (80%) had anemia and only 10 pts had normal hemoglobin above 13 gms%. About 15 patients (30%) had severe Anemia of less than 6 gm%. Among the 40 patients, 25 patients had normocytic normochronic anemia, 10 patients had microcytic anemia, and 4 patients had macrocytosis and only one had dimorphic anemia

CONCLUSION: Most common Red Blood Cell abnormality in DCLD is anemia (80%) and most common anemia is normochronic normocytic anemia (62.5%), while microcytic anemia and macrocytosis were common among females and Alcoholics, respectively

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