Author(s): Nishant Sultana1, Swati Pillai2
PURPOSE: To study the RNFL thickness measured by stratus optical coherence tomography (OCT) patients with primary open angle glaucoma (POAG) and normal subjects, analyse the quadrant which is most efficient parameter for detecting glaucomatous damage and its correlation with visual fields
MATERIAL AND METHODS: This is a cross-sectional study of 50 glaucomatous eyes and 50 normal subjects. RNFL thickness was measured in different quadrants using stratus optical coherence tomography.
RESULTS: The RNFL thickness measured by OCT in 50 glaucomatous and 50 normal eyes showed that the Inferior RNFL thickness in POAG is 77.54±31.11 compared to normal subjects where Inferior RNFL thickness is 124.96±16.74 (P<0.001). The Superior RNFL thickness in POAG is 78.32±34.81 compared to normal subjects where Superior RNFL thickness is 113.86±15.07 (P<0.001). The Nasal RNFL thickness in POAG is 53.52±13.88 compared to normal subjects where Nasal RNFL thickness is 78.103±17.87 (P<0.001). The Temporal RNFL thickness in POAG is 49.72±18.01 compared to normal subjects where Temporal RNFL thickness is 60.17±12.15 (P<0.001). The Average RNFL thickness in POAG is 63.94±18.01 compared to normal subjects where Average RNFL thickness is 97.97±9.59 (P<0.001). Both mean deviation (MD) and pattern standard deviation (PSD) showed a significant correlation with all the RNFL thickness parameters in eyes with glaucoma (pearson correlation coefficient >0.4)
CONCLUSION: RNFL thickness measured on OCT may serve as useful adjunct in accurately detecting glaucoma. Average and inferior RNFL thicknesses are among the most efficient parameters for detecting glaucoma correlating with the visual field changes.