PSYCHIATRIC COMORBIDITY IN PATIENTS WITH OPIOID DEPENDENCE

Abstract

Shihab Kattukulathil, Ajitha Cholakottil, Firoz Kazhungil, Abdurazak Kottelassal, Rahul Thovarayi, Mohammed Shafeeq Narippatta

BACKGROUND Opioid dependence is a major public health problem in Kerala. Presence of psychiatric disorder among opioid dependent patients worsens the scenario. To date no attempts have been made to analyse the magnitude and pattern of comorbid psychiatric disorders in the state. MATERIALS AND METHODS We assessed 30 patients with ICD-10 diagnosis of opioid dependence syndrome for the presence of comorbid psychiatric disorders using structured clinical interview for DSM IV Axis 1 disorder (SCID-1). Patients with opioid withdrawal state, delirium and acute medical emergencies were excluded. RESULTS 56.7% of our subjects had a comorbid psychiatric disorder. Major depressive disorder was the most common one (n=7, 23.3%). Prevalence of other disorders were generalised anxiety disorder (n=6, 20%), bipolar affective disorder (n=3, 10%) and schizophrenia (n=1, 3.3%). CONCLUSION Comorbid Psychiatric disorders are highly prevalent in opioid dependence. There is a need for further large sample studies in the areas of comorbidities and in the integrated strategies for the identification and management of both opioid dependence and comorbid psychiatric disorders.

image