PROSPECTIVE STUDY OF EFFECT OF PITAVASTATIN VERSUS ATORVASTATIN IN PATIENT WITH DYSLIPIDAEMIA

Abstract

Pasam Satish Srinivas1

BACKGROUND
Over 16 million people die each year from non-communicable disease (NCDS) between the ages of 30 and 70, of which 82% are in developing country. Out of all non-communicable diseases, cardiovascular disease is one of the important cause of death.
METHOD
Present study is designed to evaluate the efficacy of pitavastatin in hyperlipidaemia of coastal Andhra Pradesh. In this study, all patients with dyslipidaemia are enrolled; regarding diabetes mellitus patients under study, all the patients are taking same type of anti-diabetic drug. In the beginning of the study, HDL, LDL, total cholesterol and triglyceride was measured, around 40 patients were enrolled and were randomized and divided into two groups.
RESULT
Percentage change in mean of HDL in group A and B was 12.62 and 16.41. Percentage change in mean of LDL in group A and B was 17.58 and 18.47. Percentage change in mean of total cholesterol in group A and B was 19.78 and 17.96. Percentage change in mean of TG in group A and B was 21.68 and 18.12.
CONCLUSION
Regarding comparative efficacy of individual drugs except HDL concentration both are almost equally effective in reduction of total cholesterol, LDL and triglyceride. For increase in HDL, pitavastatin is more effective than atorvastatin.

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