Pragati Garg1, Ritu Karoli2, Simmi Chawla3, Nishant4
PURPOSE
To assess the association of thyroid profile with open angle glaucoma.
DESIGN
Cross-sectional observational study.
MATERIAL AND METHOD
128 cases of diagnosed thyroid disorder were enrolled. 5 cases dropped out. Ocular examination included applanation tonometry, stereoscopic optic disc photography, and automated perimetry. Correlative association of thyroid disorder and open angle glaucoma was assessed.
RESULTS
Of 123 patients of thyroid disorder, 87.8% had hypothyroidism and remaining 12.2% had hyperthyroidism. 15.74% of hypothyroidism and 20% of hyperthyroidism patients had open angle glaucoma, which was statistically significant (Pearson chi-square: Value=6.548, df=2, p=0.040). On multivariate analysis with other risk factors like female sex, family history of glaucoma, myopia, hypertension, and diabetes; it was found that hypothyroidism is an independent risk factor for open angle glaucoma.
CONCLUSION
All patients having thyroid disorder should be investigated for early diagnosis of open angle glaucoma so that if need be anti-glaucoma treatment is started at the earliest and the eye maybe saved from any further deterioration.
