PRESCRIPTION PATTERN OF ANTICANCER DRUGS IN A TERTIARY CARE HOSPITAL

Abstract

Mary Rohini Pentareddy1, A. V. S. Suresh2, Shailendra D3, Y. Subbaratnam4, G. Prasuna5, D. T. V. Naresh6, K. Rajshekar7

Carcinoma is one of the most common cause of morbidity and mortality all over the world. Chemotherapy is main stay of treatment with other modalities in the management. Present study had been conducted to evaluate prescribing pattern of anticancer drugs. An observational, retrospective study was conducted in the oncology department of ESI hospital over a period of one year. Data of patients greater than 19 years and diagnosed as carcinoma were included in the study. Out of 197 enrolled patients, majority were female (134, 68%) and in the age group of 41-60 years (147, 74.61% patients). Carcinoma of breast (58, 29.44%) was most commonly reported followed by carcinoma head and neck (46, 23.35%), and carcinoma cervix (34, 17.25%). Chemotherapy was commonly used as combination regimens (160, 81.21%). 5-Fluoro Uracil (5-FU) and platinum based combination were most frequently prescribed (60, 30.45%) especially in head and neck carcinoma (46, 23.35%). Platinum based combinations were also used in management of lung carcinoma. Dexamethasone, Ranitidine, Ondansetron, were used as palliative therapy either to prevent or manage adverse reactions of anticancer drugs.

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