Post Transfusion Purpura - Red Alert to Clinician


Harisha E.J.1, Ajeya Kashyap C.A.2, Shivakumar N.3, Siddharth Gosavi4, Garima Bhutani5

Incidence of Post Transfusion Purpura (PTP) varies between 1 : 50000 to 1 :
100000. It is a dreaded complication and needs prompt and early intervention with
high degree of clinical suspicion in the absence of serological testing to decrease
mortality. It is a rare severe complication occurring after blood transfusion. It is
characterized by severe thrombocytopenia and bleeding manifestation. It is
caused due to alloimmunization against platelet antigen, anti-HPA 1a being the
most common.