Author(s): Sridevi B1, V. Sreelakshmi2, R. Malleswari3, T. Nagaraju4
Postoperative nausea and vomiting is one of the most frequently occurring side effects affecting one third of the cases. Objective of the study was to compare the efficacy of Granisetron alone and Granisetronplus Dexamethasone in preventing post-operative nausea and vomiting after ENT surgeries. MATERIALS AND METHODS: This randomized controlled trial was conducted at the Anaesthesia and ENT departments of Santhiram Medical College and General Hospital, Nandyal from July 2014 to January 2015.60 patients belonging to physical status ASA-I and ASA-II of both sexes were selected (aged between 5-35 yrs).Patients in group-I (n=30) received Granisetron 40 mcg/kg and group –II (n=30) patients received Granisetron 40 mcg/kg and Dexamethasone 150 mcg/kg intravenously just before the start of operation. The whole postoperative period of 24 hrs was divided into 2 phases; early 0-6 hrs and late phase 6-24 hrs.