Divyashree B. N1 , Kusuma Venkatesh2 , Madhusudhan H. R3 , Hanumantha Raju B. K4

INTRODUCTION: There is an increase in the number of nephrectomies with the extensive use of imaging techniques in the recent years. In India management of chronic kidney diseases is posing a great challenge as dialysis and kidney transplantations are expensive for the patients. OBJECTIVES: 1. To analyze all the nephrectomy specimens received over a period of ten years, from 2004 to 2014 at K.I.M.S. Hospital and Research center, Bengaluru. 2. To determine the age and sex distribution in various non-neoplastic diseases. 3. To categorize the various types of non-neoplastic conditions of the kidney. MATERIALS AND METHODS: The study included retrospective and prospective cases over a period of ten years between 2004 to 2014. For the retrospective cases, blocks, slides and records were retrieved and studied. For the prospective cases, nephrectomy specimens sent for histopathological evaluation were studied. Along with routine hematoxylin - eosin stain, special stains were done when required. RESULTS: Our study included a total of 116 nephrectomy specimens of which 84(72.41%) were nonneoplastic and 32(27.59%) were neoplastic lesions. Of the 84 non-neoplastic lesions age distribution varied from 1 month to 70 years. Gender distribution included 54.76% males and 45.23 % females. The male to female ratio being 1.2:1. The commonest non-neoplastic lesion was chronic pyelonephritis (54.31%) and cystic lesions were the least. CONCLUSION: We observed that the number of nephrectomies has increased gradually over the years. Amongst non-neoplastic diseases of kidney chronic pyelonephritis is the commonest cause leading to nephrectomy.