OCULAR ADNEXAL LYMPHOMAS- A CLINICOPATHOLOGIC AND HISTOMORPHOLOGIC ANALYSIS

Abstract

Rema Priyadarsini1, Priya V. S2, Naina Jabeen Hyder3

BACKGROUND
Ocular adnexal lymphomas are mainly Non-Hodgkin’s lymphomas distributed in the conjunctiva, orbit and eyelids. These lymphomas are the commonest of the ocular adnexal lymphoid proliferations. In this study, ten cases of ocular adnexal lymphomas were analysed over a three year period.
MATERIALS AND METHODS
Comparison of clinicopathologic and histomorphologic features was done in ten cases of ocular adnexal lymphomas Immunohistochemical confirmation was obtained in six cases.
RESULTS
Of ten cases, equal incidence (40% each) was found in conjunctiva and orbit with eyelid forming 20%. Most common presentation of intraocular lymphoma was found to be decreased vision with non-resolving uveitis. Orbital tumours presented as proptosis with visible conjunctival mass. The commonest histologic type of intraocular NHL is extra nodal marginal zone lymphoma (MALT lymphoma). Primary intraocular lymphomas are unilateral and 75% cases become bilateral with central nervous system involvement and death.
CONCLUSION
The present study is a retrospective analysis of ten cases of ocular adnexal lymphomas over a period of three years. Clinicopathologic and histomorphologic analysis was done in detail. Immunohistochemical confirmation was obtained in 6 cases.

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