Author(s): Arvind Kumar1, Usha Singh2
chondrosarcoma refer to cartilage forming tumour.
Aim of the study is to find out frequency of malignant tumour of bone and to categorise the various histological type of bone cancer with respect to age, sex and site.
MATERIALS AND METHODS
This is a retrospective, nonrandomised analysis of all patients with biopsy confirmed malignant primary bone tumour including multiple myeloma and secondary metastatic bone tumour who presented between May 2015 to April 2016 in OPD of Radiation Oncology Department of Mahavir Cancer Sansthan. Epidemiological data related to patient demographics, location and histology were recorded and analysed.
In our study, 48.4% patients were suffering from primary bone tumours, 51.5% patients were having secondary bone tumour. Peak incidence of primary malignant tumour was seen in the age group of 10-19 years (48.3%) and for secondary metastatic tumour peak seen in 60-69 years of age. Male-to-female ratio were 1.8:1 in primary bone tumours, 1:2 in secondary bone tumours. Ewing’s sarcoma (41.9%) was more common than osteosarcoma (19.3%), multiple myeloma in 22.5%, malignant giant cell tumour 9.6% and chondrosarcoma in 6.4% patients. For metastatic bone tumour, most common source were of breast cancer (39.3%), followed by 21.2% uterine cervix, 15.1% head and neck cancer, 12.1% prostate cancer, 3% ovary and 3% renal cell carcinoma.
Most common bone affected in primary malignant bone tumour was femur 32.2% followed by tibia 19.3% and for secondary bone tumour vertebra 60.6% followed by pelvic bone 51.5%. Most common malignant neoplasm diagnosed was metastatic tumours of bone. Ewing’s sarcoma was the most frequent primary bone tumour in our study. The primary bone tumours was more common in males. The most common source for metastatic bone tumour was breast cancer.