MAGNESIUM SUPPLEMENTATION: IS THIS A MIRACLE DRUG TO CONTROL DIABETES-INDUCED ABNORMAL LIPID PROFILE

Abstract

Ather Akhtar Pasha1, Suhail Bin Ahmed2

BACKGROUND
Reduced levels of magnesium levels have been observed in adults who have diabetes mellitus. It was also observed in children who were supposed to have good nutritional status but were diagnosed diabetic. Low levels of serum magnesium have been linked to a number of complications that is observed in diabetes mellitus. Reduced tyrosine kinase activity has been observed. This may result in reduced insulin sensitivity. The low levels of serum magnesium may be due to glycosuria-related hypermagnesiuria, nutritional factors or hyperinsulinaemia.
Diabetic patients often have disturabances of their lipid profile. Magnesium supplementation is known to have a benificial effect on the lipid profile. The aim of the study is to find whether magnesium supplementation improves the lipid profile of the diabetic patients or not.
METHOD
The study is a cross-sectional study and the study is multi-staged.
The age criteria was not taken into consideration since all the patients belonged to the age group of 40 to 60 years.
Inclusion Criteria
1. The patients were atleast known diabetics since one year.
2. Patients were aged between 40 to 60 years.
3. Patients who were ready to be a part of this study and would come back for followup.
Exclusion Criteria
1. Patients who were known to have diabetic renal complications.
2. Patients who were on dialysis.
3. Patients who were on diuretics.
4. Patients who took magnesium antacids.
RESULT
The principle finding of this study is that the serum magnesium level is inversely related to the HbA1c, serum cholesterol, LDL and triglycerides. It is directly proportional to the HDL levels. Magnesium is known to play an important role in carbohydrate metabolism, and its imbalance has been implicated in diabetes mellitus both as a cause and a consequence.
CONCLUSION
There is a lot of scope for this study since it is slowly being understood that diabetes is not a single disease but a plethora of diseases whose dimensions are slowly being uprooted. Indeed magnesium supplementation improved the lipid profile and in the coming days it would be called a miracle drug with vast potentials.

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