Histopathological Evaluation of Endometrium in Cases of Abnormal Uterine Bleeding- An Institutional Experience in a Tertiary Care Center

Author(s): Bodhisatwa Behera1 , Saroj Ranjan Mohanty2 , Manoj Kumar Patro3 , Debi Prasad Mishra4

BACKGROUND Abnormal Uterine Bleeding (AUB) is defined as any bleeding that does not correspond with the frequency, duration or amount of blood flow of a normal menstrual cycle. It is the commonest presenting symptom and major gynaecological problem responsible for as many as one-third of all outpatient gynaecologic visit. Aim of the present study was to find out the histopathological pattern of endometrium in Abnormal Uterine Bleeding (AUB). METHODS Specimens received as endometrial curettage, and hysterectomy specimens were studied followed by correlation of histopathology with age, parity and clinical presentation. RESULTS The patients were mainly from the age group of 41 - 50 years (43.25%). Most of the patients were multiparous (81.2%). The most common menstrual disorder was menorrhagia (57.12%). In abnormal uterine bleeding the most common histological pattern of endometrium was proliferative endometrium (38.7%) followed by secretory phase (22.1%) and disordered proliferative endometrium (13.3%). Endometrial carcinoma cases were 0.5% and there was one case (0.2%) of carcinosarcoma. CONCLUSIONS Histological study of endometrium, along with a thorough clinical history and detailed physical examination, should be promptly done for every case of abnormal uterine bleeding, especially in peri- and post-menopausal women.