Vimla Kumari1, Umesh Prasad Sinha2
BACKGROUND
The beginning reason for preeclampsia is the placenta. Preeclampsia starts to lessen with the conveyance of the placenta and can happen without a baby, however, with the nearness of trophoblast tissue with hydatidiform moles. In perspective of this, investigation of the placenta ought to give knowledge into the pathophysiology of preeclampsia. In this presentation, we look at placental pathological and anatomical changes with preeclampsia and Foetal Development Limitation (FGR). No doubt, this examination ought to enlighten as both conditions are associated with comparably unusual placentation yet just in preeclampsia is there a maternal pathophysiological disorder. Comparative bits of knowledge about ahead of schedule and late onset preeclampsia ought to likewise be given by such information.
METHODS
A prospective study was led in the Department of Obstetrics and Gynaecology, Government Medical College, Bettiah. 250 instances of pregnancy actuated hypertension were concentrated on. The cases with systolic circulatory strain more prominent than 130 mmHg, diastolic pulse more noteworthy than 90 mmHg on two estimations dismantled 6 hours in relationship with histological finding were incorporated into the study. These cases were further separated as mild preeclampsia if the diastolic circulatory strain was ≤100 mmHg and as moderate preeclampsia if the diastolic pulse was 110 mmHg. Extreme cases were characterised if the systolic pulse - ≥160 mmHg, diastolic circulatory strain ≥110 mmHg. Maternal and foetal result was considered and post conveyance placenta was sent for histopathologic examination. Gross anatomical and microscopic examination was done and discoveries were connected with the seriousness of PIH.
RESULTS
Out of 250 cases, there were 156 instances of mild PIH, 53 moderate and 41 were of severe PIH. On gross examination (Table 1), the mean weight of placenta was 429.9 gm in gentle instances of PIH, 364 gm in moderate instances of PIH, and 327.86 gm in extreme instances of PIH. Histopathology of placenta is adversely co-identified with seriousness of placenta.
CONCLUSION
Placenta from the hypertension-induced pregnant women shows a significant morphological changes was observed, which may alter the perinatal outcome.
