HAEMATOLOGICAL PROFILE, SERUM IRON AND FERRITIN LEVEL IN ANAEMIA OF INFLAMMATION

Abstract

Nibedita Sahoo1, Mamita Nayak2, Pradeep Narayan Sahoo3, Radha Mohan Gharei4, Bichitrananda Roul5, Ashok Kumar Dash6

BACKGROUND
Anaemia of Chronic Disease (ACD) is the most common anaemia found in hospitalised patients and it is the second most prevalent after Iron-Deficiency Anaemia (IDA). ACD seen in patients with chronic infections, malignancy, autoimmune disorders. Condition also termed as “Anaemia of Inflammation”.
AIM AND OBJECTIVE
Combined clinical history, haematological evaluation, serum iron and ferritin estimation to reach diagnosis of ACD.
MATERIAL AND METHODS
Patients of chronic infection, autoimmune disorder, or malignancy admitted to different Departments of M.K.C.G.M.C. and Hospital are included in the study during period of 2010-2012. Routine haematological profile, ESR, serum iron, serum ferritin estimation was done.
RESULTS
80% patients have decreased serum iron, 20% normal serum iron, and 50% patients have increased S. ferritin, 40% normal S. ferritin, 10% decreased S. ferritin.
CONCLUSION
Our study emphasises anaemia of chronic disease can be diagnosed and differentiated from iron-deficiency anaemia by estimating the serum iron and ferritin level with proper clinical correlation. This can decrease the morbidity in hospitalised patients and irrational iron therapy can be avoided.

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