Abstract

EVALUATION OF INVOLVEMENT OF DIFFERENT SITES OF BRAIN BY MRI IN 1-5 YEAR AGE GROUP CHILDREN WHO SUFFERED FROM HYPOXIC ISCHAEMIC ENCEPHALOPATHY IN THE NEONATAL PERIOD

Author(s): Narayan Pandit, Asit Chandra Roy, Rajkanta Karmakar

BACKGROUND Perinatal cerebral hypoxic–ischemic insults result in neonatal brain injury with serious long-term neuro developmental sequelae. Magnetic resonance imaging (MRI) of the brain is an ideal and safe imaging modality for suspected hypoxic–ischemic injury.1 The outcome for patients with hypoxic-ischemic brain Injury (HIBI) is often poor. It is important to determine prognosis as soon as possible for better management. Clinical diagnosis is not so much helpful and ancillary investigations, particularly imaging are needed to understand the severity of brain injury and the likely outcome. MATERIALS AND METHODS 50 children who have suffered from hypoxic ischaemic encephalopathy during neonatal period were included in this study. The frequencies of involvement of different sites were evaluated by MRI of brain. RESULTS Of those 50 patients, Parieto-occipital cortex involvement seen in 16 patients. Periventricular white matter (WM) involvement seen in 7 cases, thalamus and basal ganglia involvement seen in 5 and 6 cases respectively. Subcortical WM involvement seen in 4 cases. Corpus callosum, brain-stem, and cerebellum involvement seen in 3 patients each. CONCLUSION After the data collection, we have come to a conclusion that parieto-occipital cortex has been most frequently involved among the different sites that are usually affected in HIE.