Evaluation of Indian Diabetic Risk Score and Its Association with Body Mass Index and HbA1c Levels in Mixed Urban and Rural Population of Western U.P.

Abstract

Nishant Wadhera1 , Anisha Kwatra2 , Abhishek Gupta3

BACKGROUND In the recent times, risk assessment based on anthropometric and demographic characteristics is done to identify individuals with high risk. Indian Diabetes Risk Score (IDRS) that was developed by the Madras Diabetes Research Foundation (MDRF) in the year 2005. The present study was conducted to evaluate Indian Diabetic Risk Score and its relationship with Body Mass Index and HbA1c levels in the mixed urban and rural population of Western U.P. METHODS The current study was done among 500 subjects in the Department of Medicine at Chhatrapati Shivaji Subharti Hospital from November 2018 to April 2020. HbA1c was measured for the confirmation of diabetes. Patients were interviewed and the demographic details, socioeconomic status, medical history and previous history of taking any medications and supplements were recorded. Diabetes mellitus, physical activity and diabetic score using IDRS (Indian Diabetes Risk Score) and data were collected. Anthropometric measurements such as height, weight, and waist circumference were measured. T2DM (Type 2 Diabetes Mellitus) was defined according to the criteria provided by The ADA (American Diabetes Association), as HbA1c ≥ 6.5 %. Generalized obesity was defined as BMI (Body Mass Index) ≥ 25 Kg / m2 , and for abdominal obesity (AO), the upper limit for WC of men and women was defined as 90 and 80 cms, respectively. Two???millilitre blood sample was drawn in EDTA vial for HbA1c estimation. HbA1c was measured by high???performance liquid chromatography???based method using D10 HbA1c analyser (Bio???Rad). Data so collected was analysed using SPSS version 24. RESULTS Maximum obese, overweight and normal subjects belonged to high risk, moderate risk and no risk diabetes category with statistically significant difference as p < 0.01. Out of 260 diabetic subjects, 76.92 % were at high risk, and of the 103 prediabetic subjects, 76.69 % were at moderate high risk of developing diabetes as per IDRS. Significant association was found between subjects with higher risk score and HbA1c. CONCLUSIONS Significant association was noted between Indian Diabetic Risk Score and age, systolic blood pressure, smoking, BMI and HbA1c levels in mixed urban and rural population of Western U.P.

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