Shashidhar Kallapa1, Sunayana R. Sarkar2, Gowri Shankar M3
Rhinoscleroma is a chronic inflammatory condition in which deforming masses of tissue distend the nasal cavity. Klebsiella rhinoscleromatis is the causative agent. Antibiotic therapy traditionally consisted of streptomycin and tetracycline. But long-term therapy results in adverse side effects and poor patient compliance, hence this study to search alternative agents.
MATERIALS AND METHODS
This is a prospective study of 60 cases of rhinoscleroma visiting to the Department of ENT, KIMS, for a period of two years.
After 8 weeks treatment in the atrophic and granulomatous group, 6 (60%) became histopathologically negative and 4 (40%) remained histopathologically positive. The treatment was continued for another 4 weeks in positive cases and at the end of 12 weeks, 8 (80%) turned histopathologically negative, 2 (20%) remained positive.
We conclude that ciprofloxacin is a very good alternative drug compared to doxycycline in the treatment of rhinoscleroma particularly in the early stages of the disease and complete cure can be achieved by early diagnosis and treatment.