Neostigmine with bupivacaine is widely used for improving postoperative analgesia. However, to reduce the adverse effects and to prolong post-operative intrathecal analgesia other adjuvants have been used along with neostigmine.
MATERIALS AND METHODS
Patients aged between 30 to 50 years scheduled for surgery below the umbilicus, were systematically randomized into 2 groups. Both the groups received bupivacaine with neostigmine, only group 2 received transdermal nitroglycerine patch. Both the group were assessed for vitals & duration of analgesia.
The mean age was 34.5 ± 9.51 years in group I and 36.1 ±10.4 years in group II. There was no statistically significant difference in the vitals. Duration of analgesia was longest in group II and the difference between two groups was statistically significant.
Addition of transdermal nitroglycerine patch to bupivacaine + neostigmine spinal anaesthesia produced significant increase in duration of analgesia.