EFFECT OF INTERPREGNANCY INTERVAL ON SUBSEQUENT PREGNANCY FOLLOWING A MISCARRIAGE

Abstract

Anasooya Parail Sankaran1, Rakendu Rajeev2

BACKGROUND
Primary Objective of this study was to determine the effect on interpregnancy interval on subsequent pregnancies after a miscarriage. Secondary Objective was to study the maternal and foetal complications following shorter interpregnancy interval.
MATERIALS AND METHODS
This study was done in OBG Department, Government TD Medical College, Alappuzha, during 2011 to 2013. A total of 347 cases were studied who have had a miscarriage before the current pregnancy.
RESULTS
Compared with women with an interpregnancy interval of 6-12 months, those who conceived again within six months were more likely to have another miscarriage and ectopic gestation (odds ratio 0.106, p value 0.000.). Compared with women with interpregnancy interval of <6 months, women who conceived again in 6-12 months went on to have a vaginal delivery in the second pregnancy (Odd’s ratio 0.79 and p value in is significant).Lower segment caesarean section (LSCS) is significantly high in women whose interpregnancy interval is more than 12 months (Odds ratio 0.64 and p value 0.000). Maternal complications like APH, PPH, preeclampsia, hypertension, etc. were significantly seen higher in women whose interpregnancy interval is more than 12 months (odds ratio 0.41 p value- 0.000). The women with interpregnancy interval less than 6 months didn’t develop any significant foetal complications. Most of the complications like premature rupture of membrane (PROM), meconium stained amniotic fluid (MSAF), oligamnios, foetal growth restriction (FGR), etc. are seen more in the women with interpregnancy interval 6 to 12 months odds ratio (0.30 p value significant), but breech and foetal distress are seen significantly higher in women with interpregnancy interval more than 12 months (Odds ratio 0.29 p value 0.000). Induction of labour was not significantly raised in any group.
CONCLUSION
Women who conceive within 6 months of an initial miscarriage have the best reproductive outcomes and lower complication rates in a subsequent pregnancy.

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