DOES MEAN PERFUSION PRESSURE DURING CARDIOPULMONARY BYPASS AFFECT RENAL FUNCTION?

Abstract

Ramesh Patel1 Atul Solanki2 Hasmukh Patel3 Himani Pandya4 Jignesh Patel5 Sanjay Patel6

After cardiac surgery acute kidney injury (AKI) is a common and serious condition carrying significant costs and is independently associated with increased morbidity and mortality. During cardiopulmonary bypass (CPB) surgery, modifiable factors may contribute to post-operative AKI. Their prevention might be a potential target for nephroprotection and any other morbidity after cardiac surgery.The objective of the present study was to identify and determine whether intraoperative hypotension or any other cofactor are independent risk factors for postoperative AKI defined by the RIFLE (renal Risk, Injury, Failure, Loss of renal function and End-stage renal disease). On basis of this patients were divided into two groups according to rise in serum creatinine >0.3 mg/dl till 72 hrs postoperatively. Group B patients have developed AKI (n=34) and the remaining patients were in Group A.

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