Abstract

CORRELATION OF OCULAR PERFUSION PRESSURE AND INTRAOCULAR PRESSURE CHANGES DURING HAEMODIALYSIS IN END STAGE RENAL DISEASE- AN OBSERVATIONAL STUDY

Author(s): T. R. Anuradha1, B. Radhakrishnan2, G. Nithya3, Subha Priyadarshini S4

BACKGROUND
Chronic kidney disease patients on haemodialysis have a transient raise in intraocular pressure and decrease in ocular perfusion pressure. This is used in early detection of glaucomatous optic nerve damage and subsequent irreversible visual loss.
MATERIALS AND METHODS
100 chronic kidney disease patients under haemodialysis in the nephrology department, Stanley medical college for more than one month were included in the study. We recorded complete history, and all participants were subjected to Intraocular pressure and blood pressure measurement at 3 different timings during haemodialysis session. Mean Arterial Pressure (MAP), Ocular Perfusion Pressure (OPP), Systolic Ocular Perfusion Pressure (SOPP), Diastolic Ocular Perfusion Pressure (DOPP) and Mean Ocular Perfusion Pressure (MOPP) were calculated.
RESULTS
Mean IOP from the initiation to the end of haemodialysis was found to be increased. Mean arterial pressure, ocular perfusion pressure, systolic ocular perfusion pressure, diastolic ocular perfusion pressure, mean ocular perfusion pressure was found to be decreased from the initiation to the end of haemodialysis. At the end of study period, 10% were found to develop early glaucomatous field defects and early optic nerve head changes in both eyes at follow-up.
CONCLUSION
Our study reveals the importance of screening and monitoring of intraocular pressure and characteristic early optic nerve head changes and early visual field changes of glaucoma in end-stage renal disease patients who are on haemodialysis.
KEYWORDS
Intra Ocular Pressure, Ocular Perfusion Pressure, Haemodialysis, Glaucoma.