Correlation between White Blood Cell Count and Clinical Outcome of Patients with Acute Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention

Abstract

Muhammed Shamil Mannan Purayil1 , Jesline Jose2 , Girish Parakat Vynat3 , Abdussamad Nalakath Mukkunnath4

BACKGROUND We wanted to study the correlation between white blood cell count and clinical outcome of patients with acute myocardial infarction who underwent primary percutaneous coronary intervention. METHODS A retrospective study (100 cases) was conducted at a higher cardiac center (Metromed International Cardiac Center) over a period of six months among patients who underwent PCI, to see the influence of a raised WBC count on their outcomes. The study was conducted based on a Proforma that assessed the patients on various levels and stages to derive a conclusion. RESULTS A statistically confirmed result showed that 78.5 % patients with moderate and severe LV function at presentation had raised WBC count, and on follow up 76.6 % patients with worse LV function had raised WBC count. Also 80 % of the patients with class III and class IV symptoms (NYHA) had raised WBC count. CONCLUSIONS A majority of patients who underwent Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction who had comparatively poor outcome on follow-up had raised WBC count. The WBC count at the time of presentation can be used as an independent predictor for in-hospital mortality /morbidity and post PCI outcome and may be a useful tool in assessing the prognosis of patients with acute Myocardial Infarction undergoing Primary Percutaneous Coronary Intervention in conjunction with other risk stratification factors. In this study, irrespective of the comorbidities, prognostic importance of WBC count remains relevant not only in the presentation of the patients, but also in the discharge and follow up.

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