Correlation Between Axial Length and Retinal Nerve Fiber Layer Thickness in Myopia

Author(s): Sayantan Das, Shreshth Shanker

BACKGROUND The study was designed to evaluate the anatomical changes in the eyeball that may directly affect the retinal nerve fiber layer thickness. The role of the axial length of the eyeball in the progression of myopia with stretching of the posterior segment of the eyeball has been the subject of the study. This study aimed to correlate the axial length of the eyeball with the retinal nerve fiber layer thickness in myopia. METHODS In this prospective observational study, a total of 80 myopic eyes of 40 subjects with mean age of 25.72 ± 3.01 years (range 21 to 30 years) consisting of 23 males and 17 females were recruited for the study. Careful history was taken in all the subjects. The patients were examined and refraction for the power, A scan biometry for axial length of the eyeball and Optical Coherence tomography for the measurement of circum-papillary retinal nerve fiber layer thickness were performed. RESULTS Myopia ranged from -1D to -12D (mean -3.75±2.62 D). The axial length varied from 21.98 mm to 28.68 mm (mean 24.8±3.18 mm). Average 360-degree mean RNFL thickness in cases having axial length 26 mm was 76.18±6.06 µm. CONCLUSIONS There was a significant inverse correlation associated between the anatomical anterior posterior (axial) length of the eye ball and average 360 degree circumpapillary RNFL thickness in myopic eyes.

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