COMPARISON OF ORAL TRANSMUCOSAL FENTANYL CITRATE AND INTRAMUSCULAR FENTANYL CITRATE AS PREMEDICATION FOR GENERAL ANAESTHESIA

Abstract

Darshan M. S1, Sri Devi S2

ABSTRACT: Just an imagination of getting a needle prick is frightening not only for children but also for most of the adults. Level of anxiety is generally very high in the preoperative period, and the aim of the premedication is to allay the anxiety. Premedication drugs are most commonly given parenterally and the needle phobia acts as a trigger for anxiety even though transiently. In our study 40 patients were randomized into two groups and one group received 200 microgram of trans mucosal Fentanyl and the other group received 100 microgram of Intramuscular Fentanyl (equipotent doses) as premedication and from the study we could conclude that trans mucosal Fentanyl was equally efficacious as intramuscular Fentanyl with no transient raise of pulse rate or blood pressure following administration of drug by this route.
 

image