Abstract

COMPARISION OF ROCURONIUM BROMIDE AND SUXAMETHONIUM CHLORIDE FOR USE DURING RAPID SEQUENCE INDUCTION OF ANAESTHESIA

Author(s): Sarita Chandapet 1 , Veeresham Madupathy 2 , Chendrashekar Molugu 3

To evaluate the quality of intubating conditions with Suxamethonium chloride and Rocuronium bromide for rapid sequence induction intubation and to observe the correlation between the intubating conditions and the response to single twitch stimulation. MATERIALS AND METHODS The present study, entitled “Comparison of Rocuronium bromide and Suxamethonium chloride for use during rapid sequence induction of anaesthesia was done in 50 adult patients divided into two groups and were randomly allocated Group-I: IV Rocuronium 0.9mg/kg and Group-II: IV Suxamethonium 1mg/kg. Laryngoscopy was attempted at 60 sec. and assessment of quality of intubating conditions was performed by using a Viby Mogensen Scale. Neuromuscular monitor was used to observe the correlation between the intubating conditions and the adductor pollicis response to single twitch ulnar nerve stimulation. RESULTS Intubating conditions were excellent (Score 15) in 88% of cases in Group-I whereas vocal cord position was intermediate (10- 14) in 12% of cases, in Group-II all cases could be intubated at 60 sec. (Score 15 in 100% cases). The onset of maximal blockade at adductor pollicis was found to correlate well with satisfactory intubating conditions in Group-II (Sch) whereas in 20% of patients in Group-I had single twitch response (though diminished) at the time of intubation. CONCLUSION Rocuronium bromide in dose of 0.9mg/kg provided neuromuscular blockade with a fast onset time and good to excellent intubating conditions at 60 sec. resembling those of Suxamethonium