Abstract

COMPARATIVE STUDY OF INTRANASAL MIDAZOLAM AND KETAMINE FOR PREMEDICATION IN PAEDIATRIC SURGICAL PATIENTS

Author(s): Mamta Kumari1, Suvidha Sood2, Rashmi Taneja3, Gaurav Dhir4

BACKGROUND Surgery and anaesthesia cause considerable distress and psychological consequences especially in paediatric patients. The need of the hour is to assess the efficacy of premedicant drugs given through different routes to sedate the child and alleviate stress of separation from parent and intravenous cannulation. The aim of the study was to assess efficacy of frequently administered drugs as preanaesthetic medications and pharmacologic adjuncts. MATERIALS AND METHODS A randomized double-blind clinical trial was conducted with a sample size 100 children, ASA Class I & II, aged between 2-4 years, scheduled for elective surgery after obtaining an informed written consent from the parents for the study. RESULTS The results of our study showed that intranasal ketamine is statistically better in terms of sedation, separation of child from parent and intravenous cannulation, statistically significant p value <0.5. CONCLUSION In our study, it was concluded that intranasal ketamine was statistically significantly better than midazolam in paediatric patients in producing sedation, separation from parent and intravenous cannulation in the preoperative period scheduled for surgery.