Prasanta Kumar Das1 , Bidyut Dutta2 , Jabin Musfique3 , Partha Pratim Das4
BACKGROUND A spectrum of pathological bone lesions can present in any form from inflammatory to neoplastic. These lesions are diverse in their clinical and morphological features and range in behaviour from innocuous to rapidly fatal. Accurate diagnosis, proper staging and appropriate treatment are thus necessary to ensure maximum patient survival and maintain optimal function of the affected body parts. We wanted to determine the pattern of various bone lesions and their relative frequency. METHODS This is a hospital based prospective study. After obtaining detailed clinical history, and examination, biopsies were received in 10 % formalin and histopathological examination was done. RESULTS The maximum number of bone lesions occurred in second decade of life. Out of 91 histopathologically diagnosed bone lesions, 54 (59.3%) were males and 37 (40.7 %) were females, with a male to female ratio of 1.5 : 1. Age ranged from 6 ??? 70 years. Nonneoplastic lesions accounted for 45.1 %, while neoplastic lesions accounted for 54.9 %. Chronic osteomyelitis was the most common non-neoplastic lesion encountered with 25 cases (27.4 %). Out of 50 cases of bone tumours, benign tumours accounted for 34.1 %, while malignant tumours accounted for 20.9 %. The most common benign tumour in this study was giant cell tumour and the most common malignant tumour was osteosarcoma. The most common presenting complaint of all bone lesions was pain (96.7 %) followed by swelling (75.8 %). CONCLUSIONS For precise diagnosis of majority of bone lesions, histopathology is regarded as the gold standard. A multidisciplinary approach (clinical, radiological and histopathological) is required for exact diagnosis of different lesions.
