Abstract

CLINICO-HAEMATOLOGICAL STUDY OF CHRONIC KIDNEY DISEASE IN A TERTIARY CARE CENTRE

Author(s): Parvathi Gorla1, Basumitra Das2, Bhagyalakshmi Atla3

BACKGROUND
Chronic kidney disease (CKD) is a major public health problem causing significant morbidity and mortality worldwide. Diabetes mellitus (DM) and hypertension are common causes and anaemia is a common complication. It is important to identify the cause and complication, to treat it and prevent its progression to end-stage renal disease (ESRD).
AIM
To identify the haematological pattern in chronic kidney disease patients and to study the clinical presentation.
MATERIALS AND METHODS
72 cases of CKD were studied for a period of 6 months and thorough assessment of clinical features and haematological examinations were done.
RESULTS
CKD is observed in all age groups and predominantly in older age group greater than 50 yrs., with male preponderance. DM and hypertension are common causes. 89% of the patients presented with anaemia and 4 cases of sickle cell anaemia were observed. Neutrophilic leucocytosis was seen in 29.2% and thrombocytopenia in 8.3% of cases.
CONCLUSION
CKD is seen in all age groups with a male predominance, common in older age group, anaemia being the most common and important haematological complication. Few cases of sickle cell anaemia (SCA) were seen presenting with CKD. Knowledge and treatment of these conditions has proved to improve the quality of life.